Administrative Supplements to Extend the Scope and Reach of LINCS Datasets

Posted on: February 28th, 2015 by Sherry Jenkins No Comments

This notice (NOT-RM-15-102) announces an opportunity to request administrative supplements to existing NIH research grants, to support generation of new data that will also advance the goals of the LINCS program. Please view the funding opportunities page for more details.

Call for External Collaborations with the LINCS-DCIC

Posted on: February 24th, 2015 by Avi Maayan No Comments

The LINCS DCIC announces a call for applications for the next round of external data science research projects. The call is for two year projects that would leverage LINCS generated data through application of novel computational methods. For more information, please visit: http://www.lincs-dcic.org/#/edsr. Please view the funding opportunities page for more details.

LINCS Cell Line Data Integrated into ChEMBL

Posted on: February 20th, 2015 by Sherry Jenkins No Comments

CHEMBL now provides CHEMBL IDs for all cell lines stored in their database and also cross references to the LINCS project.

chembl_screenshot

Spotlight on LINCS Information FramEwork (LIFE)

Posted on: January 28th, 2015 by Sherry Jenkins No Comments

BioGPS Spotlight on the LINCS Information FramEwork (LIFE) which is a novel knowledge-based, extensible information system of interconnected components that leverages semantic-web technologies and domain level ontologies.

The full article is posted here.

NIH Launches a United Ecosystem for Big Data

Posted on: January 8th, 2015 by Sherry Jenkins No Comments

12 Big Data to Knowledge Centers of Excellence Funded

Article about the recently funded Big Data to Knowledge Centers of Excellence was published in Biomedical Computation Review. The Data Integration and Cellular Signaling section of the article describes the BD2K-LINCS Data Coordination and Integration Center’s efforts.

The full article is posted here.

NIH invests almost $32 million to increase utility of biomedical research data

Posted on: October 9th, 2014 by Sherry Jenkins No Comments

News release published by the National Institutes of Health about the Big Data to Knowledge (BD2K) initiative. The BD2K-LINCS Data Coordination and Integration Center is one of the components of the new BD2K awards.

The BD2K-LINCS Data Coordination and Integration Center will be a data coordination center for the NIH Common Fund’s Library of Integrated Network-based Cellular Signatures (LINCS) program, which aims to characterize how a variety of types of cells, tissues and networks respond to disruption by drugs and other factors. The center will support data science research focusing on interpreting and integrating LINCS-generated data from different data types and databases in the LINCS-funded projects. This center is co-funded by BD2K and the NIH Common Fund.

http://www.nih.gov/news/health/oct2014/od-09.htm

NIH awards aim to improve understanding of cell pathways, development of new therapies

Posted on: September 11th, 2014 by Sherry Jenkins No Comments

News release published by the National Institutes of Health about the funding of six Data and Signature Generating Centers for the Library of Integrated Network-based Cellular Signatures (LINCS) program.

The LINCS program aims to catalog and analyze cellular function and molecular activity in response to perturbing agents — such as drugs and genetic factors — that are potentially disruptive to cells. LINCS researchers then will measure the cells’ tiniest molecular and biochemical responses, and use computer analyses to uncover common patterns in these responses — called “signatures.” LINCS data will be freely available to any scientist.

http://www.nih.gov/news/health/sep2014/nhgri-11.htm