LINCS Cell Categories
- cell line
- cancer cell line
- transformed cell line
- [other] immortalized cell line
- primary cell
- stem cell
- embryonic stem cell
- induced pluripotent stem cell
- differentiated cell
The teams will mainly use genotypes obtained from SNP arrays for comparison to in CCLE and with the Sanger SNP60 CGP dataset, as well as a panel of 48 SNPs to fingerprint the cell types.
For more information on the guidance being used by the LINCS teams for experimental verification, see the following article: American Type Culture Collection Standards Development Organization Workgroup ASN-0002. Cell line misidentification: the beginning of the end. Nat Rev Cancer. 2010;10:441-448. Epub 2010 May 7.